DPYSL5 Antibody Blocking Peptide(bs-23954P)-500ug

DPYSL5 Antibody Blocking Pepti

de(bs-23954P)-500ug
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  • ¥880
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  • bs-23954P
  • 2025年10月16日
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      500ug

    产品编号bs-23954P
    英文名称DPYSL5 Antibody Blocking Peptide
    中文名称二氢嘧啶酶相关蛋白5封闭多肽
    英文别名Collapsin response mediator protein 5; CRAM; CRMP 3 associated molecule; CRMP 5; CRMP3 associated molecule; Dihydropyrimidinase like 5; Dihydropyrimidinase related protein 5; DPYS L5; DPYSL 5; DPYSL5; DRP 5; DRP5; FLJ45383; Ulip 6; Ulip6; ULIP6 protein; DPYL5_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Cell Type Marker > Neuron marker > Growth Cone

    Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins

    Neuroscience > Neurology process > Neurodegenerative disease

    亚基Homotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4.
    亚细胞定位Cytoplasm.
    相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

     

     

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