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- Bioss
- bsm-30116M-PE
- 2025年10月15日
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- 规格：
25T/50T/100T
| 规格： | 25T | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 50T | 产品价格： | ￥1680.0 |
| 规格： | 100T | 产品价格： | ￥2680.0 |
| 产品编号 | bsm-30116M-PE |
| 英文名称 | human CD40 Mouse mAb, PE conjugated |
| 中文名称 | PE标记人CD40单克隆抗体 |
| 英文别名 | Tumor necrosis factor receptor superfamily, member 5; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD 40; CD40 antigen(TNF receptor superfamily member 5); CD40 antigen; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40 protein; CD40 type II isoform; CD40L receptor; CDw40; GP39; HIGM1; IGM; IMD3; MGC9013; Nerve growth factor receptor related B lymphocyte activation molecule; p50 antibody T-BAM; TBAM; TNF receptor superfamily member 5; TNR5_HUMAN; TRAP antibody Tumor necrosis factor receptor superfamily member 5; Tumor necrosis factor receptor superfamily member 5 precursor; Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a; AI326936. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 亚型 | Mouse IgG1, κ |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 30 kDa |
| 实际分子量 | 44-50kDa |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Innate and adaptive immunity Immunology > Adaptive Immunity > B Cells > CD Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage |
| 亚细胞定位 | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. |
| 组织特异性 | B-cells and in primary carcinomas. |
| 相似性 | Contains 4 TNFR-Cys repeats. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
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文献和实验[IF={{ 4.014 }}] {Tao Qin. et al. PA-X Protein of H9N2 Subtype Avian Influenza Virus Suppresses the Innate Immunity of Chicken Bone Marrow-derived Dendritic Cells. POULTRY SCIENCE. 2022 Nov;:102304} {FCM} {Chicken}
T-cell dependent antigen specific in situ staining (Pe)
and then apply 3% human serum as a blocking agent (health hazard!). 4- incubate with the blocking for 10 min. 5- blot the slides without washing and apply Phycoerythrin (B-Pe or R-Pe) 0.5µg/ml in PBS-BSA-NaN 3 , in a moist chamber, at RT for 1-18 hr.
Immunofluorescent Staining of Mouse and Rat Leukocytes
, or fluorochrome-conjugated mAbs) to predetermined optimal concentrations (see Staining Tips) in wash buffer and deliver to the wells of a U-bottom microtiter plate in a volume of 50 µl. Deliver 106 cells in 50 µl to each well already containing 50 µl of mAb
Preparation of Defined Human Embryonic Stem Cell Populations for Transcriptional Profiling
the same antigen is the antibody TG343 (Millipore, cat. no. MAB4346) PE rat anti‐mouse CD 90.2 (0.2 mg/ml; BD Pharmingen, cat. no. 553014)
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