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产品信息以Bioss网站为准
- 规格:
25T/50T/100T
| 规格: | 25T | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 50T | 产品价格: | ¥1680.0 |
| 规格: | 100T | 产品价格: | ¥2680.0 |
| 产品编号 | bsm-30116M-PE |
| 英文名称 | human CD40 Mouse mAb, PE conjugated |
| 中文名称 | PE标记人CD40单克隆抗体 |
| 英文别名 | Tumor necrosis factor receptor superfamily, member 5; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD 40; CD40 antigen(TNF receptor superfamily member 5); CD40 antigen; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40 protein; CD40 type II isoform; CD40L receptor; CDw40; GP39; HIGM1; IGM; IMD3; MGC9013; Nerve growth factor receptor related B lymphocyte activation molecule; p50 antibody T-BAM; TBAM; TNF receptor superfamily member 5; TNR5_HUMAN; TRAP antibody Tumor necrosis factor receptor superfamily member 5; Tumor necrosis factor receptor superfamily member 5 precursor; Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a; AI326936. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 亚型 | Mouse IgG1, κ |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 30 kDa |
| 实际分子量 | 44-50kDa |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Innate and adaptive immunity Immunology > Adaptive Immunity > B Cells > CD Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage |
| 亚细胞定位 | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. |
| 组织特异性 | B-cells and in primary carcinomas. |
| 相似性 | Contains 4 TNFR-Cys repeats. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
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文献和实验[IF={{ 4.014 }}] {Tao Qin. et al. PA-X Protein of H9N2 Subtype Avian Influenza Virus Suppresses the Innate Immunity of Chicken Bone Marrow-derived Dendritic Cells. POULTRY SCIENCE. 2022 Nov;:102304} {FCM} {Chicken}
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