- ￥2980
- Bioss
- bs-0841R-HRP
- 2025年10月15日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
CD28 Rabbit pAb, Cy7 conjugated(bs-1297R-Cy7)-100ul
￥2980GPCR ORF4/GPCR GPR137 Rabbit pAb, HRP conjugated(bs-16270R-HRP)-100ul
￥2980
FTHL17/CT38 Rabbit pAb(bs-16189R)-50ul/100ul/200ul
￥1180
Anti-human Mesothelin (Anetumab ravtansine Biosimilar)(BIO0887SM)-1mg/5mg/20mg
￥3200
KLK4 Rabbit pAb(bs-1965R)-50ul/100ul/200ul
￥1180
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-0841R-HRP |
| 英文名称 | GLP-2, HRP conjugated |
| 中文名称 | HRP标记的胰高血糖素样肽-2抗体 |
| 英文别名 | Glucagan-like petide; glp-2; GCG; Glicentin; Glicentin related polypeptide; GLP 2; Glucagon like peptide 2; Glucagon precursor; Glucagon preproprotein; GRPP; OXM; OXY; Oxyntomodulin; GLUC_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Cancer > Tumor biomarkers > Hormones Developmental Biology > Lineage specification > Endoderm Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones Stem Cells > Lineage Markers > Endoderm |
| 亚基 | Secreted. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. |
| 翻译后修饰 | Proglucagon is post-translationally processed in a tissue-specific manner in pancreatic A cells and intestinal L cells. In pancreatic A cells, the major bioactive hormone is glucagon cleaved by PCSK2/PC2. In the intestinal L cells PCSK1/PC1 liberates GLP-1, GLP-2, glicentin and oxyntomodulin. GLP-1 is further N-terminally truncated by post-translational processing in the intestinal L cells resulting in GLP-1(7-37) GLP-1-(7-36)amide. The C-terminal amidation is neither important for the metabolism of GLP-1 nor for its effects on the endocrine pancreas. |
| 相似性 | Belongs to the glucagon family. |
| 功能 | Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life |
| 背景资料 | Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验affinity chromatography and conjugated with horseradish peroxidase (HRP). Formulation Supplied as a 0.2 μm filtered solution in phosphate-buffered saline (PBS) (pH 7.0) with stabilizers. Storage Neat samples can be stored at 2° - 8° C
表达系统（178-541aa）：CSB-EP745804 ENL1 多克隆抗体货号（兔多抗）： No conjugated：CSB-PA745804LA01ENL HRP conjugated：CSB-PA745804LB01ENL FITC conjugated：CSB-PA745804LC01ENL Biotin conjugated：CSB-PA745804LD01ENL 参考文献： [1] Systems Genomics
溶解。但对HRP-抗HRP复合物酸化时，离子间的相互作用变弱，在这种情况下，加入少量过量的HRP，即可形成可溶性HRP-抗HRP复合物（PAP）。 [附注1] HRP与抗HRP的等价带的选择 1. 用生理盐水配制0.05mg/ml、0.1mg/m、0.15mg/ml…至3 mg/ml的HRP溶液； 2. 各稀释度HRP 0.2ml/管，分别加抗HRP血清0.2ml，混匀，4℃过夜； 3. 5000r/min离心30min； 4. 各取0.15ml上清分别加到对应的第2
技术资料暂无技术资料 索取技术资料
