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- Bioss
- bs-2658R-PE
- 2025年10月15日
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100ul
| 产品编号 | bs-2658R-PE |
| 英文名称 | CD85c Rabbit pAb, PE conjugated |
| 中文名称 | PE标记的白细胞免疫球蛋白样受体8抗体 |
| 英文别名 | Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; CD85c; CD85 antigen-like family member C; CD85c; Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LILRB5; LIR-8; LIR8; LIRB5_HUMAN |
| 产品应用 | Flow-Cyt=1μg /test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human LIR8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Detected in a natural killer (NK) cells. |
| 相似性 | Contains 4 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | May act as receptor for class I MHC antigens. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg /test} |
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文献和实验Immunofluorescence: Rabbit Anti-Murine RELMα
for 25 minutes. 3. Incubate the tissue section with blocking buffer for 20 minutes. 4. Incubate the tissue section overnight at 4?C with Rabbit Anti-Murine RELMα at 4.0 ng/mL in 1X PBS with 0.01% Triton-X and 0.5% BSA. Wash the slide
Western Immunoblotting of Proteins
antibody, a goat-anti-mouse HRP conjugated antibody is recommended, for a rabbit polyclonal antibody, a goat-anti-rabbit HRP conjugated antibody is advisable. 7. Wash the nitrocellulose membrane five times for 3 to 5 minutes each with either water
自身免疫 性疾病，其临床特点为皮肤和粘膜的自发性的、松弛性的水疱形成，病理特点是由棘层松解引起的表皮内水疱。临床上可分为寻常型（PV）、红斑型、落叶型（PE）、增殖型、疱疹样型五型。 1．免疫荧光检查 应用IIF检查，天疱疮病人中85%～90%血清中有抗表皮棘细胞间抗体（Pab）存在，活动期更高。血清中Pab滴度与病情严重程度相平行。免疫荧光图形是棘细胞间均一的线型。作IIF检查时，底物很重要。Michael等比较猴食道及豚鼠食道上皮作为PV和PF的底物
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