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FAT3 Rabbit pAb, PE conjugated

(bs-11081R-PE)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11081R-PE
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-11081R-PE
    英文名称FAT3 Rabbit pAb, PE conjugated
    中文名称PE标记的钙粘蛋白15抗体
    英文别名Cadherin family member 15; CDHF15; CDHR10; FAT tumor suppressor homolog 3; Fat3; FAT3_HUMAN; hFat3; Protocadherin Fat 3.
    产品应用IF=1:100-500, ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CDHF15/FAT3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
    组织特异性Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate.
    相似性Contains 33 cadherin domains.
    Contains 4 EGF-like domains.
    Contains 1 laminin G-like domain.
    功能May play a role in the interactions between neurites derived from specific subsets of neurons during development.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.

     

    应用推荐稀释比例
    {IF}{1:100-500}
    {ICC/IF}{1:100-500}

     

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