bs-43743P

bs-43743P

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  • ¥680 - 6880
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  • 2025年10月15日
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      20ug/100ug/500ug

    规格:20ug产品价格:¥680.0
    规格:100ug产品价格:¥2280.0
    规格:500ug产品价格:¥6880.0
    产品编号bs-43743P
    英文名称Recombinant mouse ICAM5 protein, C-His (HEK293)
    中文名称重组小鼠细胞间粘附分子5蛋白
    英文别名ICAM5_MOUSE; ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN.
    性状Liquid
    纯化方法AC
    理论分子量87.4 kDa
    浓度>1mg/ml
    储存液PBS (pH=7.4)
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Neuronal

    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
    相似性Belongs to the immunoglobulin superfamily. ICAM family.
    Contains 9 Ig-like C2-type (immunoglobulin-like) domains.
    功能ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

     

     

    bs-43743P
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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