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- 2026年10月10日
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| 规格： | 20ug | 产品价格： | ￥580.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1880.0 |
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 产品编号 | bs-42562P |
| 英文名称 | Recombinant human CNTF protein, N-His |
| 中文名称 | 重组人睫状神经营养因子蛋白 |
| 英文别名 | Ciliary Neurotrophic Factor; CNTF; CNTF_HUMAN; HCNTF. |
| 性状 | Liquid |
| 纯化方法 | AC |
| 理论分子量 | 25.2 kDa |
| 浓度 | >1mg/ml |
| 研究领域 | Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Growth and Development > Neurotrophins Stem Cells > Neural Stem Cells > Glial Restricted Lineage > Glial Progenitors |
| 亚基 | Belongs to the CNTF family. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Nervous system. |
| 相似性 | Belongs to the CNTF family. |
| 功能 | CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition to the predominant monocistronic transcript originating from this locus, the gene is also transcribed as a readthrough transcript with the upstream Zfp91 gene. The resulting protein is an isoform of Zfp91 and does not include Cntf sequence. Readthrough transcription of Zfp91 and Cntf has been observed in human and mouse. |
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文献和实验Protein‐Protein Interactions Identified by Pull‐Down Experiments and Mass Spectrometry
) formulation. Proteomics 2:486‐498. Brymora, A., Cousin, M.A., Roufogalis, B.D., and Robinson, P.J. 2001a. Enhanced protein recovery and reproducibility from pull‐down assays
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
scale. Methods Mol. Biol. 375:57‐78. Li, Q.Z., Zhou, J., Wandstrat, A.E., Carr‐Johnson, F., Branch, V., Karp, D.R., Mohan, C., Wakeland, E.K., and Olsen, N.J. 2007. Protein
Characterization of CGRP Receptor Binding
Literature Cited Aiyar, N., Disa, J., Siemens, I.R., and Nambi, P. 1997. Differential effects of guanine nucleotides on [125I]‐hCGRP(8‐37) binding to porcine
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