- ￥300 - 4000
- Bioss
- bs-48080P
- 2026年10月10日
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- 技术资料
- 规格：
10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥300.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥800.0 |
| 规格： | 500ug | 产品价格： | ￥4000.0 |
| 产品编号 | bs-48080P |
| 英文名称 | Recombinant human IFNγ protein (Active, E.coli) |
| 中文名称 | 重组人干扰素γ |
| 英文别名 | Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 理论分子量 | 16.8 |
| 储存液 | Lyophilized from a 0.22μm filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4 |
| 研究领域 | Cancer > Tumor immunology > Cytokines > Interferons Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Innate Immunity > Cytokines > Interferons Stem Cells > Signaling Pathways > TGF beta > Interferon gamma |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Released primarily from activated T lymphocytes. |
| 翻译后修饰 | Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
| 相似性 | Belongs to the type II (or gamma) interferon family. |
| 功能 | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
Measured in a cell proliferation assay using Mo7e human leukemia cell line.The ED50 for this effect is ≤2 ng/mL, corresponding to a specific activity of ≥ 2x107 units/mg.
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rHu IFNG | IFN-gamma Protein, Tag free (Active, E.coli)(bs-48080P)-10ug/50ug/500ug
￥300 - 4000
