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- bs-14635P
- 2026年10月10日
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500ug
| 产品编号 | bs-14635P |
| 英文名称 | ESPN Antibody Blocking Peptide |
| 中文名称 | 常染色体隐性遗传性耳聋型36蛋白封闭多肽 |
| 英文别名 | Autosomal recessive deafness type 36 protein; deafness autosomal recessive 36; DFNB36; ESPN_HUMAN; DKFZp434A196; DKFZp434G2126; Ectoplasmic specialization protein; ESPN; LP2654. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Auditory system Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Assembly Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins |
| 亚基 | Monomer (By similarity). Binds F-actin in a Ca(2+)-resistant fashion (By similarity). Interacts (via N-terminal) with BAIAP2 (via SH3-domain) (By similarity). Interacts with PFN2 (By similarity). |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell projection, stereocilium. Cell projection, microvillus. |
| 相似性 | Contains 9 ANK repeats. Contains 1 WH2 domain._x000D_ |
| 功能 | Espin is a multifunctional actin bundling protein. It plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament rich, microvillus type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009] |
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文献和实验相关实验
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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ESPN | DFNB36 Ab Blocking Peptide(bs-14635P)-500ug
￥880
