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| 产品编号 | bs-13441P |
| 英文名称 | GSTT2 Antibody Blocking Peptide |
| 中文名称 | 谷胱甘肽S转移酶θ2封闭多肽 |
| 英文别名 | Glutathione S Transferase theta 2; EC 2.5.1.18; Glutathione S transferase 12; Glutathione S transferase Yrs Yrs; Glutathione S-transferase theta-2; Glutathione S-transferase theta-2B; GST 12 12; GST class theta 2; GST class-theta-2; GST T2; GSTT 2; GSTT2; GSTT2 protein; GSTT2_HUMAN; GSTT2B; MGC182032; OTTHUMP00000198491; OTTHUMP00000198492. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Metabolism > Drug metabolism Signal Transduction > Metabolism > Mitochondrial |
| 亚基 | Homodimer. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. |
| 相似性 | Belongs to the GST superfamily. Theta family. _x000D_ Contains 1 GST C-terminal domain. _x000D_ Contains 1 GST N-terminal domain. |
| 功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glutathione (GSH) is a tripeptide antioxidant which reduces disulfide bonds between cytoplasmic proteins. The constitutive enzyme glutathione reductase transforms glutathione into its reduced state which ultimately can provide a measure of cellular toxicity. GSTT2 (glutathione S-transferase theta-2), also known as GST class-theta-2, is a 244 amino acid enzyme with sulfatase activity that functions in conjugating reduced glutathione to hydrophobic electrophiles. GSTT2 exists as a homodimer in the cytoplasm and is expressed in low levels in the liver and the lung. GSTT2 belongs to the GST superfamily and contains both a GST C-terminal and a GST N-terminal domain. The gene encoding GSTT2 exists on human chromosome 22. |
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文献和实验Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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