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- Bioss
- bs-12139P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12139P |
| 英文名称 | DLGAP2 Antibody Blocking Peptide |
| 中文名称 | PSD95结合蛋白2封闭多肽 |
| 英文别名 | DLGAP2; SAPAP2; DAP-2; DAP2; Discs large (Drosophila) homolog associated protein 2; Discs large homolog associated protein 2; Disks large-associated protein 2; Dlgap2; DLGP2_HUMAN; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2; hide. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Adapters |
| 亚基 | Interacts with DLG1 and DLG4/PSD-95. |
| 亚细胞定位 | Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Postsynaptic density of neuronal cells. |
| 组织特异性 | Expressed in brain and kidney. |
| 相似性 | Belongs to the SAPAP family. |
| 功能 | May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. |
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DLGAP2 | DAP-2 Ab Blocking Peptide(bs-12139P)-500ug
￥880
