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| 产品编号 | bs-12129P |
| 英文名称 | ASIC4 Antibody Blocking Peptide |
| 中文名称 | 脑钠通道蛋白4封闭多肽 |
| 英文别名 | Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary. |
| 纯化方法 | HPLC |
| 亚基 | Homotrimer or heterotrimer with other ASIC proteins. |
| 亚细胞定位 | .Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. |
| 相似性 | Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily. |
| 功能 | Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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