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SLC2A5 Antibody Blocking Pepti

de(bs-3988P)-500ug
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  • ¥880
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  • bs-3988P
  • 2025年10月16日
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      500ug

    产品编号bs-3988P
    英文名称SLC2A5 Antibody Blocking Peptide
    中文名称葡萄糖转运蛋白5封闭多肽
    英文别名GLUT-5; GLUT 5; Glucose Transporter 5 GLUT5; Glucose Transporter 5 Facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5 small intestine; SLC2A5; Solute carrier family 2; small intestine.
    纯化方法HPLC
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Signal Transduction > Metabolism > Energy Metabolism

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Membrane; Multi-pass membrane protein.
    组织特异性Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
    相似性Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
    功能Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Ten types of glucose/fructose transport carrier proteins designated as Glut 1-10 facilitate glucose/fructose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue-specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers. Glut 5 seems to function primarily as a fructose transporter; it is expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose

     

     

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