INHBA | Inhibin β-A Ab Blocking Peptide(bs-22619P)-500ug产品图

INHBA | Inhibin β-A Ab Blockin

g Peptide(bs-22619P)-500ug
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  • bs-22619P
  • 2026年10月10日
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      500ug

    产品编号bs-22619P
    英文名称INHBA Antibody Blocking Peptide
    中文名称抑制素A/Inhibin βA封闭多肽
    英文别名Activin A; Activin beta A chain; Activin beta-A chain; ActivinA; EDF; Erythroid differentiation factor; Erythroid differentiation protein; INHBA; INHBA_HUMAN; Inhibin beta A chain.
    纯化方法HPLC
    研究领域

    Cancer > Cell cycle > Cell differentiation

    Cancer > Growth factors > TGF

    Cardiovascular > Angiogenesis > Growth Factors > TGF

    Cell Biology > Cell Cycle > Cell differentiation

    Developmental Biology > Embryogenesis > Morphogens

    Developmental Biology > Lineage specification > Mesoderm

    Signal Transduction > Growth Factors/Hormones > TGF

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    Stem Cells > Lineage Markers > Mesoderm

    亚基Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3.
    亚细胞定位Secreted.
    相似性Belongs to the TGF-beta family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome

     

     

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