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- Bioss
- bs-22619P
- 2025年10月16日
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500ug
| 产品编号 | bs-22619P |
| 英文名称 | INHBA Antibody Blocking Peptide |
| 中文名称 | 抑制素A/Inhibin βA封闭多肽 |
| 英文别名 | Activin A; Activin beta A chain; Activin beta-A chain; ActivinA; EDF; Erythroid differentiation factor; Erythroid differentiation protein; INHBA; INHBA_HUMAN; Inhibin beta A chain. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell cycle > Cell differentiation Cancer > Growth factors > TGF Cardiovascular > Angiogenesis > Growth Factors > TGF Cell Biology > Cell Cycle > Cell differentiation Developmental Biology > Embryogenesis > Morphogens Developmental Biology > Lineage specification > Mesoderm Signal Transduction > Growth Factors/Hormones > TGF Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases Stem Cells > Lineage Markers > Mesoderm |
| 亚基 | Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the TGF-beta family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome |
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INHBA Antibody Blocking Peptide(bs-22619P)-500ug
￥880
