SLC2A6 | GLUT6 Ab Blocking Peptide(bs-13388P)-500ug产品图

SLC2A6 | GLUT6 Ab Blocking Pep

tide(bs-13388P)-500ug
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  • ¥880
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  • bs-13388P
  • 2026年10月10日
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      500ug

    产品编号bs-13388P
    英文名称SLC2A6 Antibody Blocking Peptide
    中文名称葡萄糖转运蛋白6封闭多肽
    英文别名Glucose Transporter GLUT6; A330096C23; F630103L12Rik; Glucose transporter type 6; GLUT-6; Glut6; GTR6_HUMAN; HSA011372; RP23-449M10.2; SLC2A6; Solute carrier family 2, facilitated glucose transporter member 6.
    纯化方法HPLC
    研究领域

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Cell membrane. The dileucine internalization motif is critical for intracellular sequestration.
    组织特异性Highly expressed in brain, spleen and peripheral blood leukocytes.
    相似性Belongs to the major facilitator superfamily.
    Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
    功能Facilitative glucose transporter; binds cytochalasin B with low affinity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The oxidation of glucose functions as the dominant source of metabolic energy for mammals. The plasma membrane is impermeable to glucose, so the cellular uptake of this important nutrient is achieved by facultative hexose transproters (Gluts). Gluts are integral membrane proteins that transport glucose and related hexoses. Glucose binds to a Glut on one side of the membrane which provokes a conformational change causing it to release glucose to the other side. Members of the Glut family may enhance the metabolic activity of tumor cells. Glut6 is part of the third out of three classes of Gluts. Glut6 is mainly expressed in the brain, spleen and peripheral leukocytes. It appears to be regulated by subcellular redistribution, because it is targeted to intracellular compartments by di-leucine motifs, recycling itself in a Dynamin-dependent manner.

     

     

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