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GLOD4 Antibody Blocking Peptid

e(bs-16250P)-500ug
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  • ¥880
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  • bs-16250P
  • 2025年10月16日
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      500ug

    产品编号bs-16250P
    英文名称GLOD4 Antibody Blocking Peptide
    中文名称GLOD4蛋白封闭多肽
    英文别名C17orf25; CGI 150; Glod4; GLOD4_HUMAN; Glyoxalase domain containing 4; glyoxalase domain containing protein 4; Glyoxalase domain-containing protein 4; HC71; my027.
    纯化方法HPLC
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Signal Transduction > Metabolism > Energy Metabolism

    亚细胞定位Mitochondrion.
    组织特异性Expressed in heart, brain, liver, kidney, pancreas and placenta. Not expressed in skeletal muscle and lung.
    相似性Belongs to the glyoxalase I family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料GLOD4 is a 313 amino acid protein belonging to the glyoxalase I family. GLOD4 interacts with NUDT9, a highly specific adenosine diphosphate ribose pyrophosphatase. Localized to mitochondrion, GLOD4 is expressed in heart, brain, liver, kidney, pancreas and placenta, but is not found in skeletal muscle or lung. Expression of GLOD4 is decreased in hepatocellular carcinoma samples in comparison to adjacent non-cancerous liver tissues from the same patients. Transfection of GLOD4 in hepatocellular carcinoma cells and overexpression has also been shown to inhibit cell growth. GLOD4 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 17p13.3.

     

     

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