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- bs-16244P
- 2025年10月16日
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500ug
| 产品编号 | bs-16244P |
| 英文名称 | GIGYF1 Antibody Blocking Peptide |
| 中文名称 | PERQ1蛋白封闭多肽 |
| 英文别名 | CDS2; GIGYF1; GRB10-interacting GYF protein 1; GYF1; PERQ amino acid-rich with GYF domain-containing protein 1; PERQ1; PERQ1_HUMAN; Postmeiotic segregation increased 2-like 12; PP3360. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases |
| 相似性 | Belongs to the PERQ family. Contains 1 GYF domain. |
| 功能 | May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PERQ1 is a 1,035 amino acid phosphoprotein that contains one GYF domain and belongs to the PERQ family. Ubiquitously expressed, PERQ1 exhibits highest expression in brain and lung, followed by heart, spleen and kidney. PERQ1 contains a GYF domain in its N-terminal half and a clathrin light chain homology domain in its C-terminal half. PERQ1 interacts with GRB10, with transient binding increased under IGF-I stimulation, thereby leading to recruitment of the PERQ1/GRB10 complex to the IGF-I receptor. PERQ1 may also increase IRS-1, Shc and IGF-I receptor phosphorylation during IGF-I stimulation, and may act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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