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- 技术资料
- 规格:
500ug
| 产品编号 | bs-3936P |
| 英文名称 | SLC27A2 Antibody Blocking Peptide |
| 中文名称 | 长链脂肪酸辅酶A连接酶封闭多肽 |
| 英文别名 | ACSVL1; FACVL1; FATP 2; FATP2; Fatty acid coenzyme A ligase, very long chain 1; Fatty acid transport protein 2; hFACVL1; HsT17226; Long chain fatty acid CoA ligase; Solute carrier family 27 (fatty acid transporter), member 2; Solute carrier family 27 member 2; THCA CoA ligase; Very long chain acyl CoA synthetase; Very long chain fatty acid CoA ligase; Very long chain fatty acid coenzyme A ligase 1; VLACS; VLCS; S27A2_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in liver, kidney, placenta and pancreas. |
| 相似性 | Belongs to the ATP-dependent AMP-binding enzyme family. |
| 功能 | Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long chain fatty acids into fatty acyl-CoA esters, and thereby may play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. |
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SLC27A2 | FATP-2 Ab Blocking Peptide(bs-3936P)-500ug
¥880






