- ￥880
- Bioss
- bs-12086P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12086P |
| 英文名称 | JAKMIP1 Antibody Blocking Peptide |
| 中文名称 | G氨基丁酸B型受体结合蛋白封闭多肽 |
| 英文别名 | FLJ31564; GABA B receptor binding protein; GABA-B receptor-binding protein; GABABRBP; Jak and microtubule interacting protein 1; JAKMIP 1; JAKMIP1; JAMIP1; Janus kinase and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; JKIP1_HUMAN; Marlin 1; Marlin-1; MARLIN1; Multiple alpha-helices and RNA-linker protein 1; Multiple coiled coil GABABR1 binding protein. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Immunology > Adaptive Immunity > T Cells > Non-CD Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > GABA Receptors Signal Transduction > Protein Phosphorylation > Tyrosine Kinases |
| 亚基 | Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2. |
| 亚细胞定位 | Cytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells. |
| 组织特异性 | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine. |
| 相似性 | Belongs to the JAKMIP family. |
| 功能 | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
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JAKMIP1 | GABABRBP Ab Blocking Peptide(bs-12086P)-500ug
￥880
