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- bs-12086P
- 2025年10月16日
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500ug
| 产品编号 | bs-12086P |
| 英文名称 | JAKMIP1 Antibody Blocking Peptide |
| 中文名称 | G氨基丁酸B型受体结合蛋白封闭多肽 |
| 英文别名 | FLJ31564; GABA B receptor binding protein; GABA-B receptor-binding protein; GABABRBP; Jak and microtubule interacting protein 1; JAKMIP 1; JAKMIP1; JAMIP1; Janus kinase and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; JKIP1_HUMAN; Marlin 1; Marlin-1; MARLIN1; Multiple alpha-helices and RNA-linker protein 1; Multiple coiled coil GABABR1 binding protein. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Immunology > Adaptive Immunity > T Cells > Non-CD Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > GABA Receptors Signal Transduction > Protein Phosphorylation > Tyrosine Kinases |
| 亚基 | Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2. |
| 亚细胞定位 | Cytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells. |
| 组织特异性 | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine. |
| 相似性 | Belongs to the JAKMIP family. |
| 功能 | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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