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ZDHHC7/ZNF370 Antibody Blockin

g Peptide(bs-12088P)-500ug
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  • ¥880
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  • bs-12088P
  • 2025年10月16日
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      500ug

    产品编号bs-12088P
    英文名称ZDHHC7/ZNF370 Antibody Blocking Peptide
    中文名称锌指蛋白370封闭多肽
    英文别名ZNF370; DHHC 7; DHHC7; FLJ10792; FLJ20279; Palmitoyltransferase ZDHHC7; ZDHHC 7; Zinc finger DHHC domain containing 7; Zinc finger DHHC domain containing protein 7; Zinc finger DHHC type containing 7; Zinc finger protein 370; ZNF 370.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Intracellular Signaling > Regulation

    Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > GABA Receptors

    Neuroscience > Neurotransmission > Secretory Vesicles > Regulation

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚细胞定位Membrane; Multi-pass membrane protein
    相似性Belongs to the DHHC palmitoyltransferase family.
    Contains 1 DHHC-type zinc finger.
    功能ZDHHC7 is a Palmitoyltransferase with broad specificity which palmitoylates SNAP25 and DLG4/PSD95 and may palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and regulate their synaptic clustering and/or cell surface stability.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

     

     

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