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- bs-17282P
- 2025年10月16日
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500ug
| 产品编号 | bs-17282P |
| 英文名称 | SCGB3A2 Antibody Blocking Peptide |
| 中文名称 | 子宫珠蛋白相关蛋白1/肺炎分泌蛋白1封闭多肽 |
| 英文别名 | LU103; Pneumo secretory protein 1; PnSP-1; PNSP1; Secretoglobin family 3A member 2; UGRP1; Uteroglobin-related protein 1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Other factors |
| 亚细胞定位 | Secreted. |
| 功能 | In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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