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- 技术资料
- 规格:
500ug
| 产品编号 | bs-17272P |
| 英文名称 | SCARF1 Antibody Blocking Peptide |
| 中文名称 | 内皮细胞清道夫受体封闭多肽 |
| 英文别名 | Acetyl LDL receptor; Endothelial cells scavenger receptor; SCARF1; Scavenger receptor class F member 1; Scavenger receptor expressed by endothelial cells 1; Scavenger receptor expressed by endothelial cells; SREC; SREC-I; SREC_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Lipoproteins Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Lipid metabolism Tags & Cell Markers > Cell Type Markers > Epi / Endo-thelial |
| 亚基 | Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is suppressed by the presence of ligand such as Ac-LDL. Interacts with AVIL (By similarity). |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Endothelial cells. |
| 相似性 | Contains 6 EGF-like domains. |
| 功能 | Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
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SCARF1 | SREC-I Ab Blocking Peptide(bs-17272P)-500ug
¥880









