eIF2D Ab Blocking Peptide(bs-14539P)-500ug产品图

eIF2D Ab Blocking Peptide(bs-1

4539P)-500ug
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  • bs-14539P
  • 2026年10月10日
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    产品编号bs-14539P
    英文名称EIF2D Antibody Blocking Peptide
    中文名称EIF2D蛋白封闭多肽
    英文别名Eukaryotic translation initiation factor 2D; HCA56; Hepatocellular carcinoma associated antigen 56; Hepatocellular carcinoma-associated antigen 56; LGTN; LIGA_HUMAN; Ligatin; OTTHUMP00000034537; OTTHUMP00000034538.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Organelle Proteins

    亚细胞定位Membrane.
    相似性Belongs to the ligatin family.
    _x000D_ Contains 1 PUA domain.
    _x000D_ Contains 1 SUI1 domain.
    功能Trafficking receptor for phosphoglycoproteins. Localizes phosphoglycoproteins within endosomes and at the cell periphery where they participate in specific metabolic processes as well as intercellular adhesion.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料HCA56 is a 584 amino acid peripheral membrane protein belonging to the ligatin family. Expressed during embryonic development and in early differentiated states, ligatin is a trafficking receptor for phosphoglycoproteins. Ligatin localizes to phosphoglycoproteins within endosomes and at the cell periphery where it participates in specific metabolic processes as well as intercellular adhesion. Involved in RNA binding and translation initiation through its single PUA domain and SUI1 domain, ligatin is down-regulated with long-lasting effects by the activation of Ca2+ dependent N-methyl-D-aspartate (NMDA) subclass of excitatory amino acid (EAA) receptors. Ligatin is considered a marker protein for membrane-vesicle transport systems. Ligatin exists as two alternatively splice variants and is encoded by a gene located on human chromosome 1.

     

     

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