- ￥880
- Bioss
- bs-22472P
- 2026年10月10日
企业认证
相关产品推荐更多 >
rHu TENT4A | PAPD7/TRF4-1 Protein, N-His(bs-104236P)-20ug/50ug/100ug
￥980
rHu LGALS2 | Gal-2 Protein, N-His(bs-42513P)-20ug/100ug/500ug
￥580rHu PDCD1 | CD279/PD-1 Protein, C-His(bs-102025P)-20ug/50ug/100ug
￥1280
AK1 Ab Blocking Peptide(bs-0299P)-500ug
￥880rHu PAPPA Protein, N-His(bs-42400P)-20ug/100ug/500ug
￥580
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
AI 赋能培养基定制开发：CHO 培养基是如何实现产量提升Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-22472P |
| 英文名称 | TTC3 Antibody Blocking Peptide |
| 中文名称 | 环指蛋白105封闭多肽 |
| 英文别名 | DCRR1; E3 ubiquitin protein ligase TTC3; E3 ubiquitin-protein ligase TTC3; Protein DCRR1; RING finger protein 105;Tetratricopeptide repeat protein 3 (TPR repeat protein D); Tetratricopeptide repeat protein 3; TPR repeat protein 3; TPR repeat protein D; TPRD; TPRDI; TPRDII; TPRDIII; TTC3; TTC3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase Neuroscience > Neurology process > Neurogenesis Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family |
| 亚基 | Interacts (when phosphorylated on Ser-378) with AKT1, AKT2 and AKT3 (when phosphorylated). Interacts with CIT. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Found in all tissues examined. |
| 翻译后修饰 | Phosphorylation on Ser-378 by Akt is required for ubiquitin ligase activity. _x000D_ _x000D_ |
| 相似性 | Contains 1 RING-type zinc finger. Contains 4 TPR repeats. |
| 功能 | E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
TTC3 | RNF105 Ab Blocking Peptide(bs-22472P)-500ug
￥880
