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| 产品编号 | bs-3850P |
| 英文名称 | TNFRSF17 Antibody Blocking Peptide |
| 中文名称 | B淋巴细胞成熟因子封闭多肽 |
| 英文别名 | B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > TNF Immunology > Immune System Diseases > Antiviral Signaling Signal Transduction > Growth Factors/Hormones > TNF |
| 亚基 | Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. |
| 亚细胞定位 | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. |
| 组织特异性 | Expressed in mature B-cells, but not in T-cells or monocytes. |
| 相似性 | Contains 1 TNFR-Cys repeat. |
| 功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq]. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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