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- Bioss
- bs-3850P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-3850P |
| 英文名称 | TNFRSF17 Antibody Blocking Peptide |
| 中文名称 | B淋巴细胞成熟因子封闭多肽 |
| 英文别名 | B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > TNF Immunology > Immune System Diseases > Antiviral Signaling Signal Transduction > Growth Factors/Hormones > TNF |
| 亚基 | Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. |
| 亚细胞定位 | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. |
| 组织特异性 | Expressed in mature B-cells, but not in T-cells or monocytes. |
| 相似性 | Contains 1 TNFR-Cys repeat. |
| 功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq]. |
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