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| 产品编号 | bs-13336P |
| 英文名称 | phospho-GFAP (Ser38) Antibody Blocking Peptide |
| 中文名称 | 磷酸化胶质纤维酸性蛋白封闭多肽 |
| 英文别名 | GFAP (phospho S38); p-GFAP (Ser38); Astrocyte; FLJ45472; GFAP; Glial Fibrillary Acidic Protein; Intermediate filament protein; GFAP_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments Neuroscience > Cell Type Marker > Glia marker > Astrocyte marker Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class II > GFAP Stem Cells > Neural Stem Cells > Glial Restricted Lineage > Astrocyte Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Glial |
| 亚基 | Interacts with SYNM. Isoform 3 interacts with PSEN1 (via N-terminus). |
| 亚细胞定位 | Cytoplasm. Note=Associated with intermediate filaments. |
| 组织特异性 | Expressed in cells lacking fibronectin. |
| 翻译后修饰 | Phosphorylated by PKN1. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
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文献和实验kinase is KIR 3.1 and have developed a phospho-selective antibody against the Y12 motif of this channel. Much like KOR and p38 MAP kinase, phosphorylation of this potassium channel increases following repeated stress. The following chapter discusses
Absorption Control in Immunohistochemistry Using Phospho-Peptides Immobilized on Magnetic Beads
neutralization of phospho-specific antibodies with phospho-peptides immobilized on magnetic beads. This technique allows for sequestration of antibody–peptide complex from the incubation solution, minimizing the risk of formation of unblocked antibodies capable
or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
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