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- Bioss
- bs-3870P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-3870P |
| 英文名称 | EVA1A Antibody Blocking Peptide |
| 中文名称 | 跨膜蛋白166封闭多肽 |
| 英文别名 | FLJ13391; TMEM 166; Transmembrane protein 166; EVA1A_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell Death > Autophagy > Signal Transduction Cancer > Signal transduction > Autophagy Cardiovascular > Heart > Autophagy Cell Biology > Apoptosis > Intracellular > Associated Proteins Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. |
| 组织特异性 | Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. |
| 相似性 | Belongs to the EVA1 family. _x000D_ |
| 功能 | Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TMEM166, also known as FAM176A (family with sequence similarity 176, member A), is a 152 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. |
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EVA1A | TMEM166 Ab Blocking Peptide(bs-3870P)-500ug
￥880
