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- 技术资料
- 规格:
500ug
| 产品编号 | bs-12059P |
| 英文名称 | CACNG3 Antibody Blocking Peptide |
| 中文名称 | 神经元电压门控钙通道γ3/L-type Ca++CP γ3封闭多肽 |
| 英文别名 | CACNG 3; Cacng2; Calcium channel voltage dependent gamma subunit 3; Neuronal voltage gated calcium channel gamma 3 subunit; Voltage dependent calcium channel gamma 3 subunit; Voltage gated calcium channel gamma subunit; CCG3_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity). |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. |
| 功能 | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CACNG3 belongs to the PMP-22/EMP/MP20 family, CACNG subfamily. It is thought to stabilize the calcium channel in an inactivated (closed) state. CACNG3 is a candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis. |
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