- ￥880
- Bioss
- bs-3829P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-3829P |
| 英文名称 | SORD Antibody Blocking Peptide |
| 中文名称 | 山梨醇脱氢酶封闭多肽 |
| 英文别名 | L iditol 2 dehydrogenase; SDH; SORD 1; SORD; SORD1. DHSO_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Alcohol metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Signal Transduction > Metabolism > Alcohol metabolism Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Mitochondrion membrane; Peripheral membrane protein. Cell projection, cilium, flagellum. Note=Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface (By similarity). |
| 组织特异性 | Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level). |
| 相似性 | Belongs to the zinc-containing alcohol dehydrogenase family. |
| 功能 | Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme. SDH is expressed almost ubiquitously in all mammalian tissues. The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states. Although SORD is closely related to the class I long-chain alcohol dehydrogenases, it differs in substrate specificity, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols. |
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SORD | SDH Ab Blocking Peptide(bs-3829P)-500ug
￥880
