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- bs-17269P
- 2026年10月10日
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500ug
| 产品编号 | bs-17269P |
| 英文名称 | SCAPER Antibody Blocking Peptide |
| 中文名称 | SCAPER蛋白封闭多肽 |
| 英文别名 | FLJ31533; FLJ31953; FLJ46212; KIAA1454; MSTP063; S phase cyclin A-associated protein in the endoplasmic reticulum; S phase cyclin A-associated protein in the ER; SCAPE_HUMAN; SCAPER; Zfp291; Zinc finger protein 291; ZNF291. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Endoplasmic reticulum. Nucleus. Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus. |
| 组织特异性 | Widely expressed with highest expression in testis. |
| 翻译后修饰 | Phosphorylated in vitro by the CCNA2/CDK2 complex. |
| 相似性 | Contains 1 C2H2-type zinc finger. |
| 功能 | CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SCAPER is a 1,399 amino acid protein that contains a C2H2-type zinc finger, a putative transmembrane domain, an ER retrieval signal at the C terminus, four coiled-coil domains, six potential RXL motifs that might confer binding to cyclins and six consensus Cdk phosphorylation sites. SCAPER interacts with, and is phosphorylated in vitro by, the cyclin A/Cdk2 complex at multiple phases of the cell cycle, including S and G2/M. It has been suggested that SCAPER represents a novel cyclin A/Cdk2 regulatory protein that transiently maintains cyclin A in the cytoplasm. The SCAPER protein is predominantly located in the endoplasmic reticulum, with only a small portion detected in the nucleus. Widely expressed, SCAPER demonstrates highest expression in testis. Existing as two alternatively spliced isoforms, the SCAPER gene is conserved in chimpanzee, dog, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q24.3. |
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文献和实验相关实验
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, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
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SCAPER Ab Blocking Peptide(bs-17269P)-500ug
￥880
