CYP2E1 | CYPIIE1 Ab Blocking Peptide(bs-1725P)-500ug产品图

CYP2E1 | CYPIIE1 Ab Blocking P

eptide(bs-1725P)-500ug
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  • bs-1725P
  • 2026年10月10日
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    • 规格:

      500ug

    产品编号bs-1725P
    英文名称CYP2E1 Antibody Blocking Peptide
    中文名称细胞色素P450ⅡE1封闭多肽
    英文别名4-nitrophenol 2-hydroxylase; CP2E1_HUMAN; CPE 1; CPE1; CYP2E; CYP2E1; CYP2E1; CYPIIE1; Cytochrome P450 2E1; cytochrome P450 family 2 subfamily E polypeptide 1; Cytochrome P450 isozyme 3A; Cytochrome P450 LM3A; Cytochrome P450 subfamily IIE (ethanol inducible) polypeptide 1; Cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; Cytochrome P450, subfamily IIE; Cytochrome P450-ALC; Cytochrome P450-J; Cytochrome P450RLM6; EC 1.14.13.-; EC 1.14.13.n7; Ethanol inducible p450; Ethanol inducible p450; Ethanol-inducible P450; flavoprotein-linked monooxygenase; MGC133529; microsomal monooxygenase; OTTHUMP00000020813; OTTHUMP00000046571; P450 ALC; P450 J; P450-J; P450C2E; P450C2E; P450J; P450RLM6; xenobiotic monooxygenase.
    纯化方法HPLC
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Alcohol metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Alcohol metabolism

    Signal Transduction > Metabolism > Drug metabolism

    亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
    组织特异性Highest level in the liver and to a lesser extent in the kidney, with a higher level in the male kidney than in the female.
    相似性Belongs to the cytochrome P450 family.
    功能Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and biosynthesis. Cytochrome P450 2E1 is induced by ethanol, diabetes and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, and exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

     

     

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