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- 2025年10月16日
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500ug
| 产品编号 | bs-17260P |
| 英文名称 | SCAI Antibody Blocking Peptide |
| 中文名称 | 肿瘤细胞转移抑制蛋白封闭多肽 |
| 英文别名 | C9orf126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Protein SCAI; SCAI; SCAI_HUMAN; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cancer > Signal transduction > G protein signaling > Small G proteins Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚基 | Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF. |
| 亚细胞定位 | Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1. |
| 相似性 | Belongs to the SCAI family. |
| 功能 | Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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