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20ug/100ug/500ug
| 规格: | 20ug | 产品价格: | ¥680.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥2280.0 |
| 规格: | 500ug | 产品价格: | ¥6880.0 |
| 产品编号 | bs-43135P |
| 英文名称 | Recombinant human GRP protein, C-hFc (HEK293) |
| 中文名称 | 重组促胃泌素释放肽蛋白 |
| 英文别名 | Gastrin releasing peptide; BN; Bombesin; GRP 10; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; preproGRP; proGRP; GRP_HUMAN. Gastrin releasing peptide precursor. |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 40.5 |
| 浓度 | >1.0mg/ml |
| 储存液 | PBS (pH7.4). |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Highly expressed both in the lateral nucleus of the amygdala, and in regions sending synaptic projections to the lateral nucleus. |
| 相似性 | ngs to the bombesin/neuromedin-B/ranatensin family. |
| 功能 | GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]. |

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文献和实验CO-IMMUNOPRECIPITATION ANALYSIS OF PROTEIN-PROTEIN INTERACTIONS
for this protocol. Transfect 2-T150s of HEK293 cells with the appropriate expression vectors (protein A and protein B) as per standard protocol. Alternatively, you can use an endogenous cell line that expressed both proteins if you have specific antibodies
Protein‐Protein Interactions Identified by Pull‐Down Experiments and Mass Spectrometry
.M., Speicher, D.W., and Wingfield, P.T. (eds.). 2003. Current Protocols in Protein Science. John Wiley & Sons, New York. Fernandez‐Patron, C., Hardy, E., Sosa, A., Seoane
Figure 5.23.3 Monitoring agonist‐promoted β‐arrestin2‐Rluc recruitment to β2AR‐EYFP and V2R‐EYFP by BRET1 . (A ) Real time BRET1 kinetics: HEK293T cells were cotransfected with pβ‐arrestin2‐hRluc and pβ2AR‐EYFP or pV
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