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- Bioss
- bs-14503P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-14503P |
| 英文名称 | EDF1 Antibody Blocking Peptide |
| 中文名称 | 内皮分化相关因子1封闭多肽 |
| 英文别名 | CAP19; EDF-1; edf1; EDF1_HUMAN; Endothelial differentiation related factor 1; Endothelial differentiation-related factor 1; MBF1; MGC9058; Multiprotein bridging factor 1; Multiprotein-bridging factor 1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription > TFIID Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin. |
| 组织特异性 | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. |
| 翻译后修饰 | Phosphorylated (by PKA and PKC). |
| 相似性 | Contains 1 HTH cro/C1-type DNA-binding domain. |
| 功能 | Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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EDF1 | MBF1 Ab Blocking Peptide(bs-14503P)-500ug
￥880
