TAGLN3 | NP25 Ab Blocking Peptide(bs-12041P)-500ug产品图

TAGLN3 | NP25 Ab Blocking Pept

ide(bs-12041P)-500ug
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  • ¥880
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  • bs-12041P
  • 2026年10月10日
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    • 规格:

      500ug

    产品编号bs-12041P
    英文名称TAGLN3 Antibody Blocking Peptide
    中文名称神经元蛋白22封闭多肽
    英文别名Neuronal protein 22; Neuronal protein NP25; NP22; NP25; TAGL3_HUMAN; TAGLN3; Transgelin 3; Transgelin-3.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Neurogenesis

    Stem Cells > Mesenchymal Stem Cells > Myogenesis

    组织特异性Widely expressed in the brain. Expression is increased in the superior frontal cortex of alcoholics, but not in the motor cortex or cerebellum.
    相似性Belongs to the calponin family.
    _x000D_ Contains 1 calponin-like repeat.
    _x000D_ Contains 1 CH (calponin-homology) domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Transgelin is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. Unlike the other two transgelin proteins, transgelin-3 (also designated TAGLN2, NP22 (neuronal protein 22) or NP25) is predominantly expressed in brain. Transgelin-3 contains a putative Actin-binding domain, two EF-hand motifs, two potential phosphorylation sites and a calponin-homology (CH) domain. Transgelin-3 shares homology with transgelin and Calponin, two cytoskeleton-interacting proteins. Belonging to the calponin family, transgelin-3 colocalizes with Actin and Tubulin, suggesting a possible role for transgelin-3 in neuronal plasticity or as a signaling protein. Due to a varied expression pattern, transgelin-3 may play different roles in the developing and adult brain. Expression of transgelin-3 is upregulated in regions of the human alcoholic brain.

     

     

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