TAS2R60 | T2R60 Ab Blocking Peptide(bs-12042P)-500ug产品图

TAS2R60 | T2R60 Ab Blocking Pe

ptide(bs-12042P)-500ug
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  • ¥880
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  • bs-12042P
  • 2026年10月10日
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    • 规格:

      500ug

    产品编号bs-12042P
    英文名称TAS2R60 Antibody Blocking Peptide
    中文名称味觉受体蛋白家族2亚基60封闭多肽
    英文别名T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell Membrane; Multi-pass membrane protein.
    组织特异性Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
    相似性Belongs to the G-protein coupled receptor T2R family.
    功能T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

     

     

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