- ￥880
- Bioss
- bs-12034P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12034P |
| 英文名称 | GODZ/ZNF373 Antibody Blocking Peptide |
| 中文名称 | 棕榈酰转移酶GODZ封闭多肽 |
| 英文别名 | DHHC-3; GABA-A receptor-associated membrane protein 1; Golgi-specific DHHC zinc finger protein; Gramp1; Palmitoyltransferase ZDHHC3; Protein DHHC1; ZDHC3; ZDHC3_HUMAN; Zdhhc3; Zinc finger DHHC domain-containing protein 3; Zinc finger protein 373; ZNF373. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Regulation Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Glutamate Receptors Neuroscience > Neurotransmitter > Transporters > GABA Signal Transduction > Protein Trafficking > Golgi Proteins Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚细胞定位 | Golgi apparatus membrane. |
| 翻译后修饰 | Autopalmitoylated. |
| 相似性 | Belongs to the DHHC palmitoyltransferase family. _x000D_ Contains 1 DHHC-type zinc finger. |
| 功能 | Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events. |
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ZDHHC3 | DHHC-3 Ab Blocking Peptide(bs-12034P)-500ug
￥880
