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| 产品编号 | bs-3764P |
| 英文名称 | DDX19B Antibody Blocking Peptide |
| 中文名称 | 解旋酶DEAD5封闭多肽 |
| 英文别名 | DDX19B; Dbp5; DDX19; DEAD box protein 19B; DEAD box RNA helicase DEAD5; helicase DEAD5; DD19B_HUMAN; ATP-dependent RNA helicase DDX19B; DEAD box RNA helicase DEAD5; DBP5; TDBP. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Nuclear Import / Export |
| 亚基 | Interacts with NUP214. |
| 亚细胞定位 | Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils. |
| 相似性 | Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| 功能 | ATP-dependent RNA helicase involved in mRNA export from the nucleus. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
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文献和实验Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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