- ￥880
- Bioss
- bs-13270P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-13270P |
| 英文名称 | GALNT10 Antibody Blocking Peptide |
| 中文名称 | 多肽N-乙酰氨基半乳糖转移酶10封闭多肽 |
| 英文别名 | DKFZp586H0623; FLJ00205; FLJ11715; GalNAc T10; GalNAc transferase 10; GalNAc-T10; GalNAcT10; GALNT10; GLT10_HUMAN; Polypeptide GalNAc transferase 10; Polypeptide N-acetylgalactosaminyltransferase 10; pp GalNAc T10; pp GaNTase 10; pp-GaNTase 10; ppGalNAcT10; ppGaNTase 10; Protein UDP acetylgalactosaminyltransferase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10. |
| 纯化方法 | HPLC |
| 研究领域 | Tags & Cell Markers > Subcellular Markers > Organelles > Golgi |
| 亚细胞定位 | Golgi apparatus membrane. |
| 组织特异性 | Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues. |
| 相似性 | Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. _x000D_ Contains 1 ricin B-type lectin domain. |
| 功能 | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues of various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T10 (Polypeptide N-acetylgalactosaminyltransferase 10), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, is a 603 amino acid single-pass type II membrane protein that prefers Muc5Ac and EA2 peptide substrates. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T10 is widely expressed, with highest levels found in small intestine. There are four isoforms of GalNAc-T10 that are produced as a result of alternative splicing events. |
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GALNT10 | GalNAc-T10 Ab Blocking Peptide(bs-13270P)-500ug
￥880
