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CETP Antibody Blocking Peptide

(bs-3694P)-500ug
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  • bs-3694P
  • 2025年10月16日
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    北京博奥森生物技术有限公司
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      500ug

    产品编号bs-3694P
    英文名称CETP Antibody Blocking Peptide
    中文名称胆固醇酯转移蛋白封闭多肽
    英文别名BPIFF; CETP; CETP_HUMAN; Cholesteryl ester transfer; Cholesteryl ester transfer protein; Cholesteryl ester transfer protein plasma; Cholesteryl ester transfer protein precursor; HDLCQ10; Lipid transfer protein I.
    纯化方法HPLC
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins

    Cardiovascular > Atherosclerosis > Lipid transport

    Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Metabolism > Types of disease > Cancer

    Metabolism > Types of disease > Heart disease

    亚细胞定位Secreted, extracellular space.
    组织特异性Expressed by the liver and secreted in plasma.
    相似性Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
    功能Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

     

     

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    CETP Antibody Blocking Peptide(bs-3694P)-500ug
    ￥880