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500ug
| 产品编号 | bs-17209P |
| 英文名称 | Junctophilin 1 Antibody Blocking Peptide |
| 中文名称 | 亲联蛋白1封闭多肽 |
| 英文别名 | DKFZp762L0313; JP 1; JP1; JPH 1; JPH1; Junctophilin 1; Junctophilin type 1; Junctophilin type1; Junctophilin1; Mitsugumin 72; Mitsugumin72. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Peripheral membrane protein (By similarity). Endoplasmic reticulum membrane; Single pass type IV membrane protein (By similarity). Sarcoplasmic reticulum membrane; Single pass type IV membrane protein. Note: Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands. |
| 功能 | JPH1 (Junctophilin 1) contributes to the stabilization of junctional membrane complexes, which are a common feature of all excitable cells and mediate cross talk between the cell surface and intracellular ion channels. It may act by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum (ER/SR). It is composed of a C terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. [provided by RefSeq, Jul 2008] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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