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EDC3 Antibody Blocking Peptide

(bs-14491P)-500ug
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  • ¥880
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  • bs-14491P
  • 2025年10月16日
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      500ug

    产品编号bs-14491P
    英文名称EDC3 Antibody Blocking Peptide
    中文名称EDC3蛋白封闭多肽
    英文别名EDC 3; edc3; EDC3_HUMAN; enhancer of mRNA decapping 3 homolog (S. cerevisiae); Enhancer of mRNA decapping 3 homolog; Enhancer of mRNA decapping 3, S. cerevisiae, homolog of; Enhancer of mRNA decapping protein 3; Enhancer of mRNA-decapping protein 3; FLJ21128; FLJ31777; hYjeF_N2; hYjeF_N2-15q23; LSM 16; LSM16; LSM16 homolog (EDC3 S. cerevisiae); LSM16 homolog (EDC3, S. cerevisiae); LSM16 homolog; YJDC; YjeF domain containing; YjeF domain containing protein 1; YjeF domain containing protein; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2; YJEFN2.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing

    亚细胞定位Cytoplasm; P-body. Processing bodies.
    组织特异性Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.
    相似性Belongs to the EDC3 family.
    Contains 1 DFDF domain.
    Contains 1 YjeF N-terminal domain.
    功能Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]Edc3, enhancer of mRNA-decapping protein 3, is a 508 amino acid protein that maps to human gene EDC3. Edc3 is a member of the EDC3 family and contains one YjeF N-terminal domain. Edc3 is localized to the cytoplasm and is found primarily in the processing bodies (PBs) of the cell. Evidence indicates Edc3 also interacts with TTP (zinc finger protein 36), a candidate gene for obesity-related metabolic complications.

     

     

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