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CBR1 Antibody Blocking Peptide

(bs-8632P)-500ug
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  • bs-8632P
  • 2025年10月16日
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      500ug

    产品编号bs-8632P
    英文名称CBR1 Antibody Blocking Peptide
    中文名称羰基还原酶1封闭多肽
    英文别名15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase; Prostaglandin E(2) 9 reductase; Prostaglandin-E(2) 9-reductase; SDR21C1.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Oxidative Stress

    Metabolism > Pathways and Processes > Cofactors, Vitamins / minerals > Vitamins / minerals

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    Signal Transduction > Metabolism > Vitamins / Minerals

    亚细胞定位Cytoplasm.
    相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    功能NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]

     

     

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