FUZ Antibody Blocking Peptide(bs-13232P)-500ug产品图

FUZ Antibody Blocking Peptide(

bs-13232P)-500ug
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  • ¥880
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  • bs-13232P
  • 2025年10月16日
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      500ug

    产品编号bs-13232P
    英文名称FUZ Antibody Blocking Peptide
    中文名称眼睛和头发颜色相关蛋白FUZ封闭多肽
    英文别名FLJ22688; fuz; FUZZY_HUMAN; Fy; Protein fuzzy homolog.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚细胞定位Cytoplasm. Cytoplasm; cytoskeleton.
    相似性Belongs to the fuzzy family.
    功能Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.

     

     

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