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| 产品编号 | bs-13232P |
| 英文名称 | FUZ Antibody Blocking Peptide |
| 中文名称 | 眼睛和头发颜色相关蛋白FUZ封闭多肽 |
| 英文别名 | FLJ22688; fuz; FUZZY_HUMAN; Fy; Protein fuzzy homolog. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚细胞定位 | Cytoplasm. Cytoplasm; cytoskeleton. |
| 相似性 | Belongs to the fuzzy family. |
| 功能 | Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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