- ￥880
- Bioss
- bs-14446P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14446P |
| 英文名称 | DUS1L Antibody Blocking Peptide |
| 中文名称 | DUS1L蛋白封闭多肽 |
| 英文别名 | 1110032N12Rik; dihydrouridine synthase 1 like (S. cerevisiae); DUS1; DUS1L; DUS1L_HUMAN; PP3111; PP3111 protein; RP23-99M13.5; tRNA-dihydrouridine synthase 1-like. |
| 纯化方法 | HPLC |
| 相似性 | Belongs to the dus family. Dus1 subfamily. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DUS1L is a 473 amino acid protein belonging to the DUS family and DUS1 subfamily that catalyzes the synthesis of dihydrouridine, a modified base located in the D-loop of many tRNAs. DUS1L binds FAD as a cofactor and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
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DUS1L Antibody Blocking Peptide(bs-14446P)-500ug
￥880
