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| 产品编号 | bs-22139P |
| 英文名称 | NR2F2 Antibody Blocking Peptide |
| 中文名称 | 载脂蛋白AI调节蛋白1封闭多肽 |
| 英文别名 | COUP transcription factor 2; COT2_HUMAN; COUP-TF2; Apolipoprotein A-I regulatory proteiARP1n 1 (ARP-1); COUP transcription factor II (COUP-TF II); Nuclear receptor subfamily 2 group F member 2; ARP1; TFCOUP2 |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2. |
| 亚细胞定位 | Nucleus (Probable). |
| 相似性 | Belongs to the nuclear hormone receptor family. NR2 subfamily. _x000D_ Contains 1 nuclear receptor DNA-binding domain |
| 功能 | Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NR2F2 is involved in the regulation of the apolipoprotein A-I gene transcription. It binds to DNA site A as a homodimer. It belongs to the nuclear hormone receptor family, NR2 subfamily. It has roles in angiogenesis, vascular remodeling and heart development. |
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文献和实验Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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