- ￥880
- Bioss
- bs-3601P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-3601P |
| 英文名称 | MTF-1 Antibody Blocking Peptide |
| 中文名称 | 金属应答元件结合转录因子-1封闭多肽 |
| 英文别名 | Metal regulatory transcription factor 1; Metal response element binding transcription factor 1; MRE binding transcription factor; Transcription factor MTF1; MTF1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger |
| 亚细胞定位 | Nucleus. |
| 相似性 | Contains 6 C2H2-type zinc fingers. |
| 功能 | Activates the metallothionein I promoter. Binds to the metal responsive element (MRE). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein. |
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MTF-1 Antibody Blocking Peptide(bs-3601P)-500ug
￥880
