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- Bioss
- bs-3528P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-3528P |
| 英文名称 | PFKFB3 Antibody Blocking Peptide |
| 中文名称 | 果糖-2,6-二磷酸酶3/磷酸果糖激酶2封闭多肽 |
| 英文别名 | PFK2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; 6-phosphofructo-2-kinase; Fructose-2,6-bisphosphatase; F263_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates Cardiovascular > Hypoxia > Hypoxia-Regulated Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Neuroscience > Neurology process > Metabolism Signal Transduction > Metabolism > Energy Metabolism |
| 组织特异性 | Ubiquitous. |
| 翻译后修饰 | Phosphorylation by AMPK stimulates activity. |
| 相似性 | In the C-terminal section; belongs to the phosphoglycerate mutase family. |
| 功能 | Synthesis and degradation of fructose 2,6-bisphosphate. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
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技术资料暂无技术资料 索取技术资料
PFKFB3 | iPFK-2 Ab Blocking Peptide(bs-3528P)-500ug
￥880
