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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-17392P |
| 英文名称 | HS3ST5 Antibody Blocking Peptide |
| 中文名称 | HS3ST5蛋白封闭多肽 |
| 英文别名 | 3-OST-5; 3OST5; h3-OST-5; Heparan sulfate (glucosamine) 3 O sulfotransferase 5; Heparan sulfate 3 OST 5; Heparan sulfate 3-O-sulfotransferase 5; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5; Heparan sulfate glucosamine 3-O-sulfotransferase 5; HS3OST5; HS3S5_HUMAN; HS3ST5; NBLA04021; Nbla04021 product like; Nbla04021 product like. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Golgi apparatus membrane. |
| 组织特异性 | Highly expressed in skeletal muscle and fetal brain, and also found in adult brain, spinal cord, cerebellum and colon. |
| 相似性 | Belongs to the sulfotransferase 1 family. |
| 功能 | Rate limiting enzyme for synthesis of HSact. Performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM, Mar 2008] |
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HS3ST5 Antibody Blocking Peptide(bs-17392P)-500ug
¥880





