- ￥880
- Bioss
- bs-0556P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-0556P |
| 英文名称 | HMGA2 Antibody Blocking Peptide |
| 中文名称 | 高迁移率族蛋白A2封闭多肽 |
| 英文别名 | HMGA 2; BABL; High mobility group (nonhistone chromosomal) protein isoform I C; High mobility group (nonhistone chromosomal) protein isoform IC; High Mobility Group AT hook 2; High Mobility Group AT hook protein 2; High mobility group protein HMGI C; High mobility group protein HMGIC; High mobility group protein I, isoform C; HMGA 2; HMGI C; HMGIC; LIPO; Non histone chromosomal architectural protein HMGI C; Non histone chromosomal architectural protein HMGIC; Pygmy; STQTL9; HMGA2_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell cycle > Cell differentiation Developmental Biology > Post embryonic development > Aging Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Epigenetics and Nuclear Signaling > Histones > HMGs Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Metabolism Neuroscience > Neurology process > Neurogenesis Stem Cells > Neural Stem Cells > Intracellular |
| 亚基 | Interacts with E4F1. Interacts with NEK2 (By similarity). |
| 亚细胞定位 | Nucleus. |
| 翻译后修饰 | Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2. |
| 相似性 | Belongs to the HMGA family.
Contains 3 A.T hook DNA-binding domains. |
| 功能 | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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HMGA2 Antibody Blocking Peptide(bs-0556P)-500ug
￥880
